SCHEMBL13428372

SCHEMBL13428372

CC1(C)c2ccccc2N(c2ccc(N3c4ccccc4C(C)(C)c4ccccc43)c3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c23)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.35
CYP2D6 P10635 2/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 6/20 0.34
MEN1 O00255 5/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPK1 P28482 1/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A2 P23975 1/20 0.34
LMNA P02545 3/20 0.33
HTT P42858 3/20 0.33
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
THRB P10828 2/20 0.32
RECQL P46063 2/20 0.32
GAA P10253 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
ACHE P22303 1/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428353 0.91 KMT2A (0.37) KMT2ACYP2D6CYP1A2MAPTMEN1
SCHEMBL13009031 0.80 ACHE (0.35) KMT2ACYP1A2MAPTMEN1KDM4E
SCHEMBL12723365 0.78 KMT2A (0.33) KMT2ACYP2D6CYP1A2MAPTMEN1
SCHEMBL13428385 0.78 P2RX4 (0.37) CYP1A2MAPTKDM4ELMNAPOLB
SCHEMBL13352833 0.77 KMT2A (0.33) KMT2ACYP2D6CYP1A2MAPTMEN1
SCHEMBL13352898 0.76 ITGB2 (0.30) KMT2ACYP2D6CYP1A2ITGB2ICAM1
SCHEMBL13371317 0.76 ITGB2 (0.30) KMT2ACYP2D6CYP1A2ITGB2ICAM1
SCHEMBL12723396 0.76 PGR (0.33) KMT2ACYP2D6CYP1A2ITGB2ICAM1
SCHEMBL13352543 0.76 KMT2A (0.32) KMT2ACYP2D6CYP1A2MAPTMEN1
SCHEMBL13428370 0.76 ACHE (0.33) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A KMT2A 2323/4885CYP2D6 1360/4885CYP1A2 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.