Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428566 | 0.85 | CCNA2 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13428499 | 0.84 | P2RX3 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13428496 | 0.84 | NR1H4 (0.34) | ALDH1A1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL8194345 | 0.84 | CCNA2 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13428522 | 0.84 | CCNA2 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13429157 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8178636 | 0.82 | TGFBR1 (0.37) | ALDH1A1NPC1RAB9AL3MBTL1TGFBR1 | |
| SCHEMBL13428587 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13428532 | 0.81 | MCHR1 (0.35) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4221748 | 0.81 | CCNA2 (0.38) | MEN1KMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | HDAC1, HDAC11, HDAC2 | ALDH1A1 1516/4885MEN1 2025/4885KMT2A 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.