Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 12/20 | 0.66 |
| ▸ | CA1 | P00915 | 12/20 | 0.66 |
| ▸ | CA2 | P00918 | 12/20 | 0.66 |
| ▸ | CA9 | Q16790 | 12/20 | 0.66 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420330 | 0.88 | ALDH1A1 (0.56) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3417215 | 0.88 | CA1 (0.56) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3421164 | 0.87 | CA12 (0.64) | CA12CA1CA2CA9CA4 | |
| SCHEMBL13111190 | 0.85 | CA1 (0.53) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3473383 | 0.85 | CA1 (0.53) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3472037 | 0.85 | FFAR4 (0.55) | CA12CA1CA2CA9CA4 | |
| SCHEMBL2404366 | 0.85 | CA1 (0.56) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1824434 | 0.84 | FFAR4 (0.57) | CA12CA1CA2CA9CA4 | |
| SCHEMBL13637114 | 0.84 | CA1 (0.52) | CA12CA1CA2CA9CA4 | |
| SCHEMBL13429353 | 0.84 | CA1 (0.60) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045505-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2010-04-22 | — | — | WO | disclosed |