Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | PI4KA | P42356 | 2/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13429427 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL19258528 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL13456716 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL858866 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL5995916 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL29381813 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL23547977 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL859095 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL22112122 | 0.89 | PI4K2A (0.53) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL14946285 | 0.89 | PI4K2A (0.53) | ADORA3ADORA2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912318-B2 | Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids | UNIVERSITY OF IDAHO (US) | 2014-12-16 | — | — | US | disclosed |
| US-20130123481-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-05-16 | — | — | US | disclosed |
| US-20120295862-A1 | NUCLEOBASE-FUNCTIONALIZED CONFORMATIONALLY RESTRICTED NUCLEOTIDES AND OLIGONUCLEOTIDES FOR TARGETING OF NUCLEIC ACIDS | The Univeristy of Idaho | 2012-11-22 | — | — | US | disclosed |
| US-20100062994-A1 | Adenosine Receptor Antagonists | SANTARIS PHARMA A/S (DK) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123481-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | ADAR, NT5C3B, NSUN2 | ADORA3 103/4885ADORA2A 85/4885PI4KA 2533/4885 |
| US-20120295862-A1 | NUCLEOBASE-FUNCTIONALIZED CONFORMATIONALLY RESTRICTED NUCLEOTIDES AND OLIGONUCLEOTIDES FOR TARGETING OF NUCLEIC ACIDS | NT5C3B, UNG, NT5C2 | ADORA3 201/4885ADORA2A 145/4885PI4KA 4589/4885 |
| US-20100062994-A1 | Adenosine Receptor Antagonists | ADORA3, ADORA2A, ADORA1 | ADORA3 1/4885ADORA2A 2/4885PI4KA 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.