SCHEMBL13429682

SCHEMBL13429682

CO[Si](OC)(OC)c1cc(Br)cc(Br)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PRNP P04156 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13429746 0.86 ALDH1A1 (0.33) ALDH1A1PRNPMAPTNPSR1RXFP1
SCHEMBL13429737 0.84 ALDH1A1 (0.40) HSD17B10ALOX15ALOX12CA2CA4
SCHEMBL574581 0.80 ALDH1A1 (0.32) ALDH1A1
SCHEMBL13429719 0.78 IDO1 (0.33) IDO1
SCHEMBL13429605 0.77 CA2 (0.44) CA2CA4MAPTNPSR1
SCHEMBL13429725 0.77 POLB (0.36)
SCHEMBL2324534 0.77 ALDH1A1 (0.43) ALDH1A1MAPTIDO1
SCHEMBL13429689 0.75 TP53 (0.35) ALDH1A1MAPT
SCHEMBL13429666 0.75
SCHEMBL1115633 0.74 CYP2A6 (0.42) ALOX15ALDH1A1MAPTNPSR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed