SCHEMBL574581

SCHEMBL574581

CO[Si](OC)(OC)c1cc([Si](OC)(OC)OC)cc([Si](OC)(OC)OC)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13027827 0.88 ACHE (0.40) ALDH1A1
SCHEMBL18762841 0.86 TDP1 (0.44) ALDH1A1
SCHEMBL13027804 0.86 ALDH1A1 (0.50) ALDH1A1
SCHEMBL574627 0.82 ACHE (0.32) ALDH1A1
SCHEMBL2891726 0.82 ACHE (0.40) ALDH1A1
SCHEMBL2891674 0.80 TUBB1 (0.33)
SCHEMBL13027141 0.80 ALDH1A1 (0.58) ALDH1A1
SCHEMBL13429682 0.80 HSD17B10 (0.32) ALDH1A1
SCHEMBL15735963 0.80 CA12 (0.33)
SCHEMBL50828 0.79 KDM4E (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190015815-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION 2019-01-17 US claimed
EP-3426388-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2019-01-16 EP claimed
EP-2598440-A2 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2013-06-05 EP claimed
EP-2598441-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2013-06-05 EP claimed
WO-2012018598-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2012-02-09 WO claimed
WO-2012018596-A2 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2012-02-09 WO claimed
US-12623205-B2 Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution WATERS TECHNOLOGIES CORPORATION (US) 2026-05-12 US disclosed
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography WATERS TECHNOLOGIES CORPORATION (US) 2026-04-28 US disclosed
EP-3834927-B1 METHOD FOR PREPARING A SUPERFICIALLY POROUS MATERIAL WATERS TECHNOLOGIES CORP (US) 2026-03-25 EP disclosed
US-20250387778-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2025-12-25 US disclosed
EP-3426390-B1 POROUS MATERIALS WITH CONTROLLED POROSITY AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORP (US) 2025-12-17 EP disclosed
EP-4353682-B1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION, USEFUL FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORP (US) 2025-11-12 EP disclosed
US-12427502-B2 Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations WATERS TECHNOLOGIES CORPORATION (US) 2025-09-30 US disclosed
US-20100096009-A1 POROUS SILICA, OPTICAL-PURPOSE LAYERED PRODUCT AND COMPOSITION, AND METHOD FOR PRODUCING POROUS SILICA MITSUBISHI CHEMICAL CORPORATION (JP) 2010-04-22 US disclosed
EP-2130797-A1 SILICA POROUS BODY, LAMINATE AND COMPOSITION FOR OPTICAL USE, AND METHOD FOR PRODUCING SILICA POROUS BODY Mitsubishi Chemical Corporation (JP) 2009-12-09 EP disclosed
US-20090066220-A1 Electroluminescent device MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-12 US disclosed
US-20090066219-A1 Electroluminescent device MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-12 US disclosed
US-7462984-B2 Electroluminescent device with a low refractive layer and a light scattering layer MITSUBISHI CHEMICAL CORPORATION (JP) 2008-12-09 US disclosed
US-20060049745-A1 Electroluminescent device MITSUBISHI CHEMICAL CORPORATION (JP) 2006-03-09 US disclosed
EP-1603367-A1 ELECTROLUMINESCENCE DEVICE Mitsubishi Chemical Corporation (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography F11, F12, F2 ALDH1A1 493/4885
US-12623205-B2 Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution ZYX, FGB, F11 ALDH1A1 4087/4885
US-20250387778-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS C1S, C9, C1R ALDH1A1 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.