SCHEMBL13430010

SCHEMBL13430010

Cc1cc(S)c(OCc2ccc(F)cc2)c(Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.44
MAPT P10636 6/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAOB P27338 4/20 0.43
THRB P10828 2/20 0.43
THRA P10827 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
KMT2A Q03164 3/20 0.41
BRD4 O60885 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
GRM5 P41594 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PAX8 Q06710 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
MEN1 O00255 2/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13429881 0.85 LMNA (0.46) LMNAMAPTNPSR1THRBTHRA
SCHEMBL13429977 0.85 THRB (0.48) LMNAMAPTMAOBTHRBTHRA
SCHEMBL12440965 0.85 MAPT (0.49) LMNAMAPTNPSR1MAOBTHRB
SCHEMBL13429911 0.85 MAOB (0.49) MAPTMAOBTHRBTHRA
SCHEMBL12514198 0.81 LMNA (0.46) LMNAMAPTNPSR1MAOBTHRB
SCHEMBL9893587 0.80 THRB (0.44) LMNAMAPTNPSR1MAOBTHRB
SCHEMBL13429707 0.79 KMT2A (0.44) LMNAMAPTNPSR1MAOBTHRB
SCHEMBL13429949 0.78 MAOB (0.51) MAOBTHRBTHRASMN1; SMN2ALDH1A1
SCHEMBL9946068 0.78 THRB (0.42) LMNAMAPTNPSR1MAOBTHRB
SCHEMBL13430008 0.77 MAPT (0.46) LMNAMAPTNPSR1MAOBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed