SCHEMBL12440965

SCHEMBL12440965

Cc1cc(C)c(OCc2ccc(F)cc2)c(Br)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
THRB P10828 2/20 0.48
THRA P10827 1/20 0.48
LMNA P02545 7/20 0.47
NPSR1 Q6W5P4 1/20 0.45
MAOB P27338 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 2/20 0.43
BRD4 O60885 1/20 0.42
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41
GRM5 P41594 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PAX8 Q06710 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13430010 0.85 LMNA (0.44) MAPTTHRBTHRALMNANPSR1
SCHEMBL12440960 0.84 THRA (0.51) MAPTL3MBTL1THRBTHRALMNA
SCHEMBL12440971 0.84 MEN1 (0.55) MAPTL3MBTL1THRBTHRALMNA
SCHEMBL12514198 0.84 LMNA (0.46) MAPTTHRBTHRALMNANPSR1
SCHEMBL12440963 0.84 MAOB (0.51) MAPTL3MBTL1THRBTHRALMNA
SCHEMBL9893587 0.82 THRB (0.44) MAPTTHRBTHRALMNANPSR1
SCHEMBL13429707 0.81 KMT2A (0.44) MAPTL3MBTL1THRBTHRALMNA
SCHEMBL9946068 0.80 THRB (0.42) MAPTTHRBTHRALMNANPSR1
SCHEMBL12440978 0.77 THRA (0.56) MAPTL3MBTL1THRBTHRALMNA
SCHEMBL12440961 0.76 MAPT (0.50) MAPTL3MBTL1THRBTHRALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAPT 456/4885L3MBTL1 4308/4885THRB 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.