Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 2/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430247 | 0.89 | TNNI3K (0.40) | EGFRMEN1KMT2AHTR1AADRA1D | |
| SCHEMBL13399926 | 0.84 | EGFR (0.43) | EGFRMAPK10PRKCIBRD3P2RX3 | |
| SCHEMBL13430250 | 0.84 | PTGS2 (0.44) | EGFRMAPK10MEN1KMT2A | |
| SCHEMBL13429857 | 0.80 | TNNI3K (0.38) | EGFRMEN1KMT2AHTR1AADRA1D | |
| SCHEMBL13430284 | 0.77 | CCNE1 (0.32) | EGFR | |
| SCHEMBL13430211 | 0.73 | AURKA (0.39) | EGFR | |
| SCHEMBL13399924 | 0.73 | AURKA (0.45) | EGFRMEN1KMT2AHTR1AADRA1D | |
| SCHEMBL13430291 | 0.72 | AURKA (0.49) | EGFR | |
| SCHEMBL13430208 | 0.72 | AURKA (0.37) | EGFRKMT2A | |
| SCHEMBL13430207 | 0.72 | AURKA (0.39) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036629-A2 | FUSED MULTICYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-04-01 | — | — | WO | disclosed |