Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.43 |
| ▸ | AURKA | O14965 | 14/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 10/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13429733 | 0.92 | ADK (0.48) | ADKAURKAAURKB | |
| SCHEMBL13430256 | 0.91 | ADK (0.43) | ADKAURKAAURKBRPS6KB1 | |
| SCHEMBL13429734 | 0.82 | AURKA (0.53) | ADKAURKAAURKB | |
| SCHEMBL13399807 | 0.81 | AURKA (0.60) | ADKAURKAAURKB | |
| SCHEMBL13399977 | 0.79 | AURKA (0.63) | ADKAURKAAURKBRPS6KB1 | |
| SCHEMBL13625873 | 0.76 | AURKA (0.65) | AURKAAURKB | |
| SCHEMBL13430270 | 0.76 | KDR (0.40) | AURKAAURKBRPS6KB1 | |
| SCHEMBL13625779 | 0.76 | AURKA (0.65) | AURKAAURKB | |
| SCHEMBL13399985 | 0.74 | AURKA (0.52) | ADKAURKAAURKB | |
| SCHEMBL13625527 | 0.74 | AURKA (0.45) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036629-A2 | FUSED MULTICYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-04-01 | — | — | WO | disclosed |