Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430540 | 0.87 | LMNA (0.32) | — | |
| SCHEMBL13561414 | 0.81 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL29352110 | 0.81 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL225186 | 0.81 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL4689632 | 0.78 | CHRNB2 (0.41) | ESR1ESR2 | |
| SCHEMBL29761239 | 0.76 | CHRNB2 (0.46) | ESR1ESR2 | |
| SCHEMBL3564889 | 0.76 | CHRNB2 (0.46) | ESR1ESR2 | |
| SCHEMBL4407063 | 0.76 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL6395748 | 0.75 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL224375 | 0.74 | ESR1 (0.45) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062046-A1 | POLYMORPHS OF NICOTINIC INTERMEDIATES | ALLEN DOUGLAS J M | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062046-A1 | POLYMORPHS OF NICOTINIC INTERMEDIATES | NAPRT, NAMPT, NNMT | ESR1 3551/4885ESR2 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.