Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377617 | 0.90 | LMNA (0.40) | P2RX3P2RX2LMNAPLAUCHRNB2 | |
| SCHEMBL14530741 | 0.84 | CYP2C9 (0.41) | P2RX3P2RX2PLAUMAOBMAPK14 | |
| SCHEMBL3291059 | 0.78 | MAOB (0.43) | P2RX3P2RX2MAOBTAS1R3TAS1R1 | |
| SCHEMBL2288990 | 0.76 | KDM4E (0.43) | LMNAMAOAMAOBALDH1A1HPGD | |
| SCHEMBL3289602 | 0.75 | L3MBTL1 (0.43) | HDAC1HDAC6P2RX3P2RX2CHRNB2 | |
| SCHEMBL12377620 | 0.75 | MAOB (0.38) | MAOAMAOBKAT6A | |
| SCHEMBL12379047 | 0.75 | MMP1 (0.37) | P2RX3P2RX2MAOAMAOBCHRNB2 | |
| SCHEMBL3304686 | 0.75 | CYP2C9 (0.39) | P2RX3P2RX2MAOBMAPK14TAS1R3 | |
| SCHEMBL3306956 | 0.75 | CYP2C9 (0.39) | P2RX3P2RX2MAOBMAPK14TAS1R3 | |
| SCHEMBL3292761 | 0.75 | NPC1 (0.47) | P2RX3P2RX2ALDH1A1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069499-A1 | AMIDE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069499-A1 | AMIDE COMPOUND AND USE THEREOF | CBR1, CBR3, GBA1 | HDAC1 159/4885HDAC6 508/4885P2RX3 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.