Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 9/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433216 | 0.91 | KMT2A (0.47) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| Bromide SCHEMBL8471510 | 0.90 | HSP90AA1 (0.50) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| Bromide SCHEMBL8469213 | 0.84 | HSP90AA1 (0.48) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| SCHEMBL3426726 | 0.83 | ALDH1A1 (0.41) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| SCHEMBL8469225 | 0.81 | ALDH1A1 (0.48) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| Bromide SCHEMBL8469899 | 0.80 | KEAP1 (0.45) | ALDH1A1KEAP1NFE2L2MAPTTP53 | |
| Bromide SCHEMBL8076530 | 0.78 | KEAP1 (0.46) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| SCHEMBL8470105 | 0.78 | ALDH1A1 (0.43) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| SCHEMBL8144928 | 0.78 | TP53 (0.64) | KMT2AALDH1A1F2HPGDHSP90AA1 | |
| Bromide SCHEMBL8469666 | 0.78 | KEAP1 (0.48) | ALDH1A1KEAP1NFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695980-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-04-13 | — | — | US | disclosed |