Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 8/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471272 | 0.94 | ALDH1A1 (0.46) | ALDH1A1KMT2AF2HPGDHSP90AA1 | |
| SCHEMBL8469659 | 0.91 | LMNA (0.51) | ALDH1A1KMT2AKEAP1NFE2L2MAPT | |
| Bromide SCHEMBL8471510 | 0.88 | HSP90AA1 (0.50) | ALDH1A1KMT2AF2HPGDHSP90AA1 | |
| SCHEMBL8076269 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KMT2AF2HPGDHSP90AA1 | |
| SCHEMBL8470816 | 0.88 | KEAP1 (0.42) | KEAP1NFE2L2LMNAKDM4E | |
| SCHEMBL8470105 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KMT2AF2HPGDHSP90AA1 | |
| Bromide SCHEMBL8469213 | 0.84 | HSP90AA1 (0.48) | ALDH1A1KMT2AF2HPGDHSP90AA1 | |
| SCHEMBL8076560 | 0.83 | MMP3 (0.42) | ALDH1A1KMT2AF2HPGDHSP90AA1 | |
| SCHEMBL8470011 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDKEAP1NFE2L2MAPT | |
| SCHEMBL8471286 | 0.82 | LMNA (0.45) | ALDH1A1KMT2AHSP90AA1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |