Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23291847 | 0.87 | NT5E (0.36) | NT5ETTRHDAC6RORCSMN1; SMN2 | |
| SCHEMBL30112575 | 0.86 | NT5E (0.41) | NT5ETTRHDAC6RORCSMN1; SMN2 | |
| SCHEMBL24942496 | 0.86 | NT5E (0.41) | NT5ETTRHDAC6RORCSMN1; SMN2 | |
| SCHEMBL13435046 | 0.83 | KMT2A (0.53) | NT5ETTRRORCSMN1; SMN2HPGD | |
| SCHEMBL18526322 | 0.83 | NT5E (0.41) | NT5ETTRHDAC6RORCSMN1; SMN2 | |
| SCHEMBL18526325 | 0.81 | NT5E (0.40) | NT5ETTRHDAC6RORCOPRM1 | |
| SCHEMBL995937 | 0.81 | FTO (0.49) | NT5ETTRRORCHPGDKCNH2 | |
| SCHEMBL24942508 | 0.80 | NT5E (0.40) | NT5ETTRHDAC6RORCSMN1; SMN2 | |
| SCHEMBL30112567 | 0.80 | NT5E (0.40) | NT5ETTRHDAC6RORCSMN1; SMN2 | |
| SCHEMBL34465270 | 0.79 | PRMT1 (0.49) | NT5ETTRHDAC6RORCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816180-A1 | CIRCULARLY PERMUTATED HALOALKANE TRANSFERASE FUSION MOLECULES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-05-05 | — | — | EP | disclosed |