SCHEMBL13435495

SCHEMBL13435495

CCCCCCCNC(=O)[C@H]1CN(C2CC2)[C@@H](CCCNC(=N)N)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 3/20 0.43
▸ GNAI3 P08754 2/20 0.37
▸ GNAO1 P09471 2/20 0.37
▸ GNAI1 P63096 2/20 0.37
▸ NAAA Q02083 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ SPHK1 Q9NYA1 3/20 0.34
▸ ALB P02768 1/20 0.34
▸ SIRT2 Q8IXJ6 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ SIRT3 Q9NTG7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12236156 0.92 ALB (0.34) PRCPALB
SCHEMBL13611172 0.91 ALB (0.34) PRCPALB
SCHEMBL12572183 0.87 PRCP (0.43) PRCPGNAI3GNAO1GNAI1NAAA
SCHEMBL18288918 0.86 SIRT2 (0.31) SIRT2SIRT1SIRT3
SCHEMBL13611169 0.85 FURIN (0.31) —
SCHEMBL12236129 0.85 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL13611124 0.85 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL13611181 0.85 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL13499207 0.85 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL12236104 0.85 SIRT2 (0.32) SIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2010-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA PRCP 494/4885GNAI3 2172/4885GNAO1 2338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback