Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 7/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847210 | 0.88 | IDO1 (0.33) | IDO1ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL9320556 | 0.86 | IDO1 (0.32) | IDO1ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL7774002 | 0.86 | ALDH1A1 (0.34) | ALDH1A1CYP2C9HPGDALOX15ALOX12 | |
| SCHEMBL1884733 | 0.83 | ALDH1A1 (0.35) | IDO1LMNAALDH1A1CYP2C9HPGD | |
| SCHEMBL6535277 | 0.79 | ALDH1A1 (0.38) | LMNAALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL10885589 | 0.76 | HPGD (0.40) | LMNAALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL6438083 | 0.75 | HPGD (0.39) | LMNAALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL15056135 | 0.75 | HPGD (0.37) | ALDH1A1CYP2C9HPGDALOX15ALOX12 | |
| SCHEMBL9845551 | 0.75 | CHRM2 (0.35) | ALDH1A1CYP2C9HPGDALOX15ALOX12 | |
| SCHEMBL11039571 | 0.75 | HSD17B10 (0.35) | TP53LMNAALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062993-B2 | Developer mixture for thermal recording materials and thermal recording materials | API CORPORATION (JP) | 2011-11-22 | — | — | US | disclosed |