SCHEMBL6535277

SCHEMBL6535277

CCN(CC)c1cc(C)c(Nc2ccccc2)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
ALOX12 P18054 2/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
BRCA1 P38398 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
FTO Q9C0B1 3/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
SMAD3 P84022 1/20 0.32
KMT2A Q03164 1/20 0.32
PRMT1 Q99873 1/20 0.32
ACE2 Q9BYF1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535472 0.93 ALDH1A1 (0.34) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL7774002 0.92 ALDH1A1 (0.34) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL15056135 0.92 HPGD (0.37) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL5681921 0.92 ALDH1A1 (0.34) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL10772026 0.91 ALDH1A1 (0.34) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL4750113 0.90 ALDH1A1 (0.36) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL5684606 0.89 RAPGEF4 (0.43) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL16430376 0.89 ALDH1A1 (0.38) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL4777360 0.89 CYP3A4 (0.34) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL10885589 0.89 HPGD (0.40) ALDH1A1HPGDALOX12CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115579-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION Ciba SC Holding AG (CH) 2001-07-18 EP claimed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO claimed
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP disclosed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
EP-0410206-A1 Fluoran compounds, crystalline toluene adducts thereof, recording material comprising same and process for their preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-01-30 EP disclosed
EP-0405363-A2 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-01-02 EP disclosed
EP-0400485-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-12-05 EP disclosed
EP-0384665-A2 Optical recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-08-29 EP disclosed
EP-0372325-A2 Recording material BAYER AG (DE) 1990-06-13 EP disclosed
EP-0344705-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-12-06 EP disclosed