SCHEMBL9847210

SCHEMBL9847210

CCCN(c1cc(C)c(Nc2ccccc2)c2c1C(=O)OC21c2ccccc2Oc2ccccc21)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
DRD2 P14416 3/20 0.31
DRD1 P21728 3/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320556 0.95 IDO1 (0.32) IDO1ALDH1A1CYP2C9HPGDALOX15
SCHEMBL1343587 0.88 IDO1 (0.34) IDO1ALDH1A1CYP2C9HPGDALOX15
SCHEMBL1884733 0.87 ALDH1A1 (0.35) IDO1ALDH1A1CYP2C9HPGDALOX15
SCHEMBL15056135 0.85 HPGD (0.37) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL6438083 0.85 HPGD (0.39) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL4750113 0.82 ALDH1A1 (0.36) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL6535277 0.81 ALDH1A1 (0.38) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL10587427 0.80 ALDH1A1 (0.35) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL10885589 0.80 HPGD (0.40) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL5681921 0.79 ALDH1A1 (0.34) ALDH1A1CYP2C9HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0411509-A2 Fluoran compound, process for preparation thereof and heat sensitive recording materials comprising said compound MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-02-06 EP disclosed