SCHEMBL134373

SCHEMBL134373

CC(NC(=O)CI)Nc1cccc2c(S(=O)(=O)O)cccc12

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
TTR P02766 1/20 0.40
USP30 Q70CQ3 6/20 0.36
CASP6 P55212 1/20 0.35
ATIC P31939 1/20 0.34
EDNRA P25101 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
SNCA P37840 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040342 0.84 TTR (0.48) CYP1A2TTRCASP6ATICALDH1A1
Sulfuric Acid SCHEMBL6255048 0.83 ANPEP (0.46) CYP1A2ALDH1A1
SCHEMBL9627393 0.81 CASP6 (0.60) CYP1A2CASP6ALDH1A1POLBSNCA
SCHEMBL3931602 0.80 ANPEP (0.50) CYP1A2ALDH1A1
SCHEMBL18268230 0.79 TTR (0.50) CYP1A2TTRUSP30CASP6ATIC
SCHEMBL18260692 0.76 TTR (0.51) CYP1A2TTRCASP6ATICSNCA
SCHEMBL25745 0.75 CA12 (0.44) CYP1A2TTRCASP6ALDH1A1SNCA
SCHEMBL29358898 0.75 CA12 (0.44) CYP1A2TTRCASP6ALDH1A1SNCA
SCHEMBL29355645 0.75 CA12 (0.44) CYP1A2TTRCASP6ALDH1A1SNCA
SCHEMBL8928010 0.75 ANPEP (0.36) CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4247968-A1 USE OF DEXTRAMER IN SINGLE CELL ANALYSIS Becton, Dickinson and Company (US) 2023-09-27 EP claimed
CN-116615556-A Use of DEXTRAMER in single cell assays 贝克顿迪金森公司 2023-08-18 CN claimed
WO-2022109339-A1 USE OF DEXTRAMER IN SINGLE CELL ANALYSIS BECTON, DICKINSON AND COMPANY (US) 2022-05-27 WO claimed
US-20220064226-A1 Panel comprising Borrelia MHC multimers IMMUDEX APS (DK) 2022-03-03 US claimed
EP-3898666-A2 PANEL COMPRISING BORRELIA MHC MULTIMERS Immudex ApS (DK) 2021-10-27 EP claimed
WO-2020127222-A2 PANEL COMPRISING BORRELIA MHC MULTIMERS IMMUDEX APS (DK) 2020-06-25 WO claimed
US-20140087401-A1 Biomarkers for Assessment of the Molecular Quality in Biospecimens VORTMEYER ALEXANDER OLIVER (US) 2014-03-27 US claimed
US-8431356-B2 Fluorescence resonance energy transfer assays for sarco/endoplasmic reticulum calcium atpase and phospholamban REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2013-04-30 US claimed
EP-1458760-B1 ENTRAPPED BINDING PROTEINS AS BIOSENSORS BECTON DICKINSON CO (US) 2012-03-07 EP claimed
EP-2337795-A2 MHC MULTIMERS IN CANCER VACCINES AND IMMUNE MONITORING Dako Denmark A/S (DK) 2011-06-29 EP claimed
US-6815423-B1 SUBSTANCE P POLYPEPTIDE COMPRISING LIGHT EMITTING MOIETY; PERKINELMER LAS, INC. 2004-11-09 US claimed
EP-1468023-A2 BINDING PROTEINS AS BIOSENSORS Becton, Dickinson and Company (US) 2004-10-20 EP claimed
US-20040072369-A1 Methods for assaying for urea and kits for use therein UNIVERSITY OF MARYLAND, BALTIMORE 2004-04-15 US claimed
US-6680367-B1 LIGHT EMITTING COMPOUNDS; PROBES; RECEPTOR BINDING ASSAYS ADVANCED BIOCONCEPT COMPANY (CA) 2004-01-20 US claimed
US-6677430-B1 POLYPEPTIDES LINKED TO LABELS USED AS DETECTORS OR KITS FOR MONITORING OR ANALYZING BIOLOGICAL RECEPTORS ADVANCED BIOCONCEPT COMPANY (CA) 2004-01-13 US claimed
US-20030153026-A1 Entrapped binding protein as biosensors BECTON, DICKINSON AND COMPANY 2003-08-14 US claimed
US-20030134346-A1 Glucose biosensor; mutated binding protein with a reporter group attached that provides detectable and reversible signal change when exposed to varying glucose concentrations BECTON, DICKINSON AND COMPANY 2003-07-17 US claimed
WO-2003057851-A2 BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2003-07-17 WO claimed
EP-1059531-A1 Labelling of peptides and proteins Nordheim, Alfred, Prof. Dr. (DE) 2000-12-13 EP claimed
US-4942136-A Method for production of fluorescence-labeled Fab' AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-07-17 US claimed