Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.56 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437316 | 0.87 | L3MBTL1 (0.60) | CDC7DBF4FBP1KDM4EALDH1A1 | |
| SCHEMBL13437315 | 0.86 | CDC7 (0.58) | CDC7DBF4L3MBTL1TRPM8 | |
| SCHEMBL20022399 | 0.83 | CDC7 (0.62) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL13437330 | 0.83 | TRPM8 (0.47) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL13437332 | 0.82 | TRPM8 (0.56) | CDC7DBF4KDM4EALDH1A1MAPT | |
| SCHEMBL13437328 | 0.81 | TRPM8 (0.49) | CDC7DBF4KDM4EMAPTMEN1 | |
| SCHEMBL289392 | 0.81 | CDC7 (0.60) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL289684 | 0.81 | CDC7 (0.60) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL13437321 | 0.81 | TRPM8 (0.61) | LMNAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL13437333 | 0.81 | TRPM8 (0.61) | CDC7DBF4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2030974-B1 | THIAZOLE NON-NUCLEOSIDE COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND THEIR USE AS ANTIVIRAL AGENTS | SHANGHAI INST MATERIA MEDICA (CN) | 2016-02-17 | — | — | EP | disclosed |
| US-8653115-B2 | Heterocyclic non-nucleoside compounds, their preparation, pharmaceutical composition and their use as antiviral agents | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-18 | — | — | US | disclosed |
| US-8653115-B2 | Heterocyclic non-nucleoside compounds, their preparation, pharmaceutical composition and their use as antiviral agents | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-18 | — | — | US | disclosed |
| US-20100056569-A1 | Heterocyclic Non-Nucleoside Compounds, Their Preparation, Pharmaceutical Composition And Their Use As Antiviral Agents | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-03-04 | — | — | US | disclosed |
| US-20100056569-A1 | Heterocyclic Non-Nucleoside Compounds, Their Preparation, Pharmaceutical Composition And Their Use As Antiviral Agents | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-03-04 | — | — | US | disclosed |
| EP-2030974-A1 | HETEROCYCLIC NON-NUCLEOSIDE COMPOUNDS, THEIR PEPARATION, PHARMACEUTICAL COMPOSITION AND THEIR USE AS ANTIVIRAL AGENTS | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056569-A1 | Heterocyclic Non-Nucleoside Compounds, Their Preparation, Pharmaceutical Composition And Their Use As Antiviral Agents | TYMP, PNP, NUDT1 | CDC7 1256/4885DBF4 471/4885FBP1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.