Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252131 | 0.80 | CXCR2 (0.56) | DRD2DRD3DRD4MAPTLMNA | |
| SCHEMBL2556708 | 0.80 | CXCR2 (0.56) | DRD2DRD3DRD4MAPTLMNA | |
| SCHEMBL252140 | 0.79 | CXCR2 (0.55) | DRD2DRD3MAPTACHE | |
| Hydrochloric Acid SCHEMBL253136 | 0.79 | CXCR2 (0.55) | DRD2DRD3DRD4MAPTLMNA | |
| SCHEMBL251855 | 0.79 | CXCR2 (0.55) | DRD2DRD3MAPTACHE | |
| Hydrochloric Acid SCHEMBL5569882 | 0.78 | CXCR2 (0.54) | DRD2DRD3MAPTACHE | |
| Hydrochloric Acid SCHEMBL251520 | 0.78 | CXCR2 (0.54) | DRD2DRD3MAPTACHE | |
| SCHEMBL1819154 | 0.75 | MAPK1 (0.41) | DRD2DRD3DRD4LMNAMAPK1 | |
| SCHEMBL3584598 | 0.74 | CXCR2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL252769 | 0.73 | CXCR2 (0.58) | DRD2DRD3DRD4ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440711-B2 | 2-aryl-2-fluoropropanoic acids and derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-8440711-B2 | 2-aryl-2-fluoropropanoic acids and derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-20100076034-A1 | 2-ARYL-2-FLUOROPROPANOIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE PHA.R.MA S.P.A. (IT) | 2010-03-25 | — | — | US | disclosed |
| US-20100076034-A1 | 2-ARYL-2-FLUOROPROPANOIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE PHA.R.MA S.P.A. (IT) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076034-A1 | 2-ARYL-2-FLUOROPROPANOIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FPR2, FPR3, FPR1 | DRD2 3775/4885DRD3 3852/4885DRD4 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.