Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543102 | 0.79 | ADORA3 (0.48) | ADORA3CYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31410645 | 0.78 | MAPT (0.60) | CYP1A2GAAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL10622390 | 0.77 | RELA (0.52) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL12120523 | 0.77 | TXNRD1 (0.47) | MAPTKMT2AMEN1NPSR1MAPK1 | |
| SCHEMBL11072978 | 0.76 | MERTK (0.55) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11545271 | 0.76 | MAPT (0.49) | GAAMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4728549 | 0.75 | RELA (0.43) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11544441 | 0.73 | KMT2A (0.51) | GAAMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13439484 | 0.72 | CYP1A2 (0.50) | ADORA3CYP1A2SMN1; SMN2LMNAHTT | |
| SCHEMBL11545397 | 0.72 | XDH (0.45) | MAPTSMN1; SMN2KMT2ANPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |