SCHEMBL1343992

SCHEMBL1343992

COc1c2occc2c(O)c2c(=O)cc(C)oc12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.78
CYP1A1 P04798 3/20 0.78
HPGD P15428 3/20 0.78
MAPK1 P28482 3/20 0.78
ALDH1A1 P00352 3/20 0.78
CYP1A2 P05177 2/20 0.78
CYP1B1 Q16678 2/20 0.78
CYP2D6 P10635 1/20 0.78
PDE4A P27815 1/20 0.78
CYP2C19 P33261 1/20 0.78
SMN1; SMN2 Q16637 1/20 0.78
KCNA3 P22001 2/20 0.59
PTGS1 P23219 4/20 0.56
PTGS2 P35354 4/20 0.56
ADORA3 P0DMS8 1/20 0.55
THRB P10828 1/20 0.55
MAPT P10636 1/20 0.54
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
PPARG P37231 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Khellin SCHEMBL9655 0.88 CYP3A4 (1.00) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
Khellin SCHEMBL30839911 0.88 CYP3A4 (1.00) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL3609628 0.86 CYP3A4 (0.82) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL1341546 0.85 CYP3A4 (0.55) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL1344606 0.84 CYP3A4 (0.78) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL12133302 0.84 CYP3A4 (0.56) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL10300855 0.83 CYP3A4 (0.53) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL10300858 0.83 ALDH1A1 (0.56) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL4037947 0.82 CYP3A4 (0.56) CYP3A4CYP1A1HPGDMAPK1ALDH1A1
SCHEMBL13920849 0.81 CYP3A4 (0.81) CYP3A4CYP1A1HPGDMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11083197-B2 Herbicidal composition comprising chromone derivatives and a method for weed control Investigaciones Biologicas en Agroquimicos Rosario S.A. (AR) 2021-08-10 US claimed
US-20190021328-A1 HERBICIDAL COMPOSITION COMPRISING CHROMONE DERIVATIVES AND A METHOD FOR WEED CONTROL INVESTIGACIONES BOLÓGICAS EN AGROQUIMICOS ROSARIO S.A. (AR) 2019-01-24 US claimed
EP-3397056-A1 HERBICIDAL COMPOSITION COMPRISING CHROMONE DERIVATIVES AND A METHOD FOR WEED CONTROL Investigaciones Biológicas en Agroquimicos Rosario S.A. (AR) 2018-11-07 EP claimed
WO-2017115333-A1 HERBICIDAL COMPOSITION COMPRISING CHROMONE DERIVATIVES AND A METHOD FOR WEED CONTROL INVESTIGACIONES BIOLÓGICAS EN AGROQUÍMICOS ROSARIO S.A. (AR) 2017-07-06 WO claimed
US-20260034186-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2026-02-05 US disclosed
US-12427176-B2 Enriched mineral pitch resin products and methods of manufacturing enriched mineral pitch resin products RIZUN NODARI (US) 2025-09-30 US disclosed
US-20240216456-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-07-04 US disclosed
US-20240216457-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-07-04 US disclosed
US-20240207344-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-06-27 US disclosed
US-20240207342-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-06-27 US disclosed
US-20240108676-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-04-04 US disclosed
US-11883454-B2 Enriched mineral pitch resin products and methods of manufacturing enriched mineral pitch resin products RIZUN NODARI (US) 2024-01-30 US disclosed
US-20080221194-A1 Novel Potassium channel Blockers and Uses Thereof HARVEY ANDREW J 2008-09-11 US disclosed
US-20080221194-A1 Novel Potassium channel Blockers and Uses Thereof HARVEY ANDREW J 2008-09-11 US disclosed
WO-2006096911-A1 NOVEL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF HARVEY ANDREW J (AU) 2006-09-21 WO disclosed
EP-0303920-B1 BENZOFURAN DERIVATIVES AND THERAPEUTIC AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1992-03-18 EP disclosed
EP-0284914-B1 BENZOFURAN DERIVATIVES AND THERAPEUTIC AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1991-10-16 EP disclosed
US-4845096-A Benzofuran derivatives and antiulcerogenic agents containing same BASF AKTIENGSELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0303920-A1 Benzofuran derivatives and therapeutic agents containing them BASF Aktiengesellschaft (DE) 1989-02-22 EP disclosed
EP-0284914-A1 Benzofuran derivatives and therapeutic agents containing them BASF Aktiengesellschaft (DE) 1988-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11083197-B2 Herbicidal composition comprising chromone derivatives and a method for weed control CBR3, CYP4B1, CHRM1 CYP3A4 38/4885CYP1A1 12/4885HPGD 951/4885
US-20190021328-A1 HERBICIDAL COMPOSITION COMPRISING CHROMONE DERIVATIVES AND A METHOD FOR WEED CONTROL CBR3, CYP4B1, CHRM1 CYP3A4 38/4885CYP1A1 12/4885HPGD 951/4885
US-20260034186-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS TRPV1, SOST, RUNX1 CYP3A4 1979/4885CYP1A1 2153/4885HPGD 1580/4885
US-20080221194-A1 Novel Potassium channel Blockers and Uses Thereof KCNAB1, KCNB1, KCNMB1 CYP3A4 2095/4885CYP1A1 1790/4885HPGD 3279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.