Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301332 | 0.87 | THRB (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29633266 | 0.83 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9109 | 0.83 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL3332893 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Water SCHEMBL7762373 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Water SCHEMBL10709467 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL2584553 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL17200169 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Ammonia Solution, Strong SCHEMBL7767435 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL4098212 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037127-A1 | CHROMENONE ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2010-04-01 | — | — | WO | disclosed |