SCHEMBL13446104

SCHEMBL13446104

O=C1c2ccccc2C(=O)c2c1nc1ccc(Br)cn21

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.63
HSP90AB1 P08238 1/20 0.63
TDO2 P48775 1/20 0.44
PARP1 P09874 1/20 0.44
AKT1 P31749 1/20 0.43
AKT2 P31751 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
AHR P35869 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTR6 P50406 1/20 0.41
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40
PRNP P04156 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8465416 0.90 HSP90AA1 (0.50) HSP90AA1HSP90AB1PARP1AKT1AKT2
SCHEMBL8465227 0.82 HSP90AA1 (0.63) HSP90AA1HSP90AB1TDO2PARP1AKT1
SCHEMBL8464925 0.82 HSP90AA1 (0.63) HSP90AA1HSP90AB1TDO2PARP1AKT1
SCHEMBL8465390 0.82 HSP90AA1 (0.63) HSP90AA1HSP90AB1TDO2AKT1AKT2
SCHEMBL1274825 0.78 HSP90AA1 (1.00) HSP90AA1HSP90AB1ALDH1A1
SCHEMBL13411347 0.76 HSP90AA1 (0.56) HSP90AA1HSP90AB1TDO2CYP1A2CYP3A4
SCHEMBL13411348 0.75 HSP90AA1 (0.55) HSP90AA1HSP90AB1AKT1AKT2CYP1A2
SCHEMBL8468193 0.73 HSP90AA1 (0.51) HSP90AA1HSP90AB1TDO2PARP1AKT1
SCHEMBL8466530 0.72 HSP90AA1 (0.50) HSP90AA1HSP90AB1TDO2AKT1AKT2
SCHEMBL31237237 0.72 HSP90AA1 (0.50) HSP90AA1HSP90AB1PARP1AKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7678474-B2 Imidazole derivatives and organic electronic device using the same LG CHEM. LTD. (KR) 2010-03-16 US disclosed