Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | AKT2 | P31751 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411347 | 0.81 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1DHODHCYP1A2CYP3A4 | |
| SCHEMBL8465227 | 0.75 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1AKT1AKT2CYP1A2 | |
| SCHEMBL13446104 | 0.75 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1AKT1AKT2CYP1A2 | |
| SCHEMBL8464925 | 0.75 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1AKT1AKT2CYP1A2 | |
| SCHEMBL8465390 | 0.75 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1DHODHAKT1AKT2 | |
| SCHEMBL13411349 | 0.75 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL8931006 | 0.73 | ALDH1A1 (0.44) | HSP90AA1HSP90AB1DHODHAKT1CYP1A2 | |
| SCHEMBL1274825 | 0.71 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL1429195 | 0.69 | AKT1 (0.63) | AKT1AKT2NPC1RAB9A | |
| SCHEMBL8468193 | 0.67 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1AKT1AKT2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678474-B2 | Imidazole derivatives and organic electronic device using the same | LG CHEM. LTD. (KR) | 2010-03-16 | — | — | US | disclosed |
| US-7678474-B2 | Imidazole derivatives and organic electronic device using the same | LG CHEM. LTD. (KR) | 2010-03-16 | — | — | US | disclosed |
| US-20070018154-A1 | Imidazole derivatives and organic electronic device using the same | LG CHEM. LTD. (KR) | 2007-01-25 | — | — | US | disclosed |
| US-20070018154-A1 | Imidazole derivatives and organic electronic device using the same | LG CHEM. LTD. (KR) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070018154-A1 | Imidazole derivatives and organic electronic device using the same | ICMT, KCND3, INMT | HSP90AA1 3796/4885HSP90AB1 4076/4885DHODH 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.