Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12602049 | 0.95 | ESR1 (0.54) | ESR1ESR2CHRM5ACHEHTT | |
| SCHEMBL11949430 | 0.88 | ESR1 (0.47) | ESR1ESR2CHRM5ALDH1A1MAPT | |
| SCHEMBL822520 | 0.87 | ESR1 (0.52) | ESR1ESR2CHRM5TNFSF11HTT | |
| SCHEMBL14287530 | 0.81 | ESR1 (0.49) | ESR1ESR2CHRM5MAPTNPC1 | |
| SCHEMBL11949428 | 0.81 | FPR1 (0.37) | ESR1ESR2CHRM5ALDH1A1MAPT | |
| SCHEMBL17148016 | 0.80 | BACE1 (0.44) | ESR1ESR2TNFSF11HTTALDH1A1 | |
| SCHEMBL22651232 | 0.79 | ESR1 (0.70) | ESR1ESR2CHRM5HTTALDH1A1 | |
| SCHEMBL21075509 | 0.77 | ESR1 (0.49) | ESR1ESR2CHRM5HTTALDH1A1 | |
| SCHEMBL17791453 | 0.76 | ESR1 (0.48) | ESR1ESR2HTTALDH1A1MAPT | |
| SCHEMBL18415977 | 0.76 | ESR1 (0.61) | ESR1ESR2CHRM5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956792-B2 | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of producing electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20120263494-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2012-10-18 | — | — | US | disclosed |