SCHEMBL1344667

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4812956	0.90	PBRM1 (0.55)	MAOAMAOBPBRM1HSD17B1KDM4E
	SCHEMBL7542462	0.89	MAOA (0.46)	MAOAMAOBCYP2A6PRKCIPBRM1
	SCHEMBL11949158	0.83	MAOA (0.52)	MAOAMAOBCYP2A6PRKCIPBRM1
	SCHEMBL31512087	0.80	FFAR4 (0.50)	MAOAMAOBMAPK1
	SCHEMBL7535153	0.80	FFAR4 (0.50)	MAOAMAOBMAPK1
	SCHEMBL3171240	0.79	MAOA (0.55)	MAOAMAOBCYP2A6PRKCIPBRM1
	SCHEMBL12678151	0.79	MAOA (0.55)	MAOAMAOBCYP2A6PRKCIPBRM1
	SCHEMBL1346675	0.79	AKR1B1 (0.52)	MAOAMAOBCYP2A6PRKCIPBRM1
	SCHEMBL10523260	0.78	MAOA (0.48)	MAOAMAOBCYP2A6
	SCHEMBL7998432	0.78	ALDH1A1 (0.47)	KDM4EALDH1A1ALOX5GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.