Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.81 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.81 |
| ▸ | PTGES2 | Q9H7Z7 | 8/20 | 0.81 |
| ▸ | PTGES | O14684 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | USP2 | O75604 | 3/20 | 0.81 |
| ▸ | TP53 | P04637 | 3/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.81 |
| ▸ | RECQL | P46063 | 3/20 | 0.81 |
| ▸ | BLM | P54132 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351963 | 0.90 | PTGES2 (1.00) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL503001 | 0.90 | PTGES2 (1.00) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL1193211 | 0.90 | ALOX5 (0.85) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL9670560 | 0.89 | ALOX5 (0.79) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL170216 | 0.89 | ALOX5 (0.76) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL9457522 | 0.89 | PTGES2 (1.00) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL9457520 | 0.89 | ALOX5 (0.77) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL16857038 | 0.88 | ALOX5 (1.00) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL1193441 | 0.87 | ALOX5 (0.72) | ALOX5ALOX5APPTGES2PTGESMEN1 | |
| SCHEMBL9187373 | 0.86 | ALOX5 (0.75) | ALOX5ALOX5APPTGES2PTGESMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068301-A1 | COMPOSITIONS AND TREATMENTS COMPRISING 5-LIPOXYGENASE-ACTIVATING PROTEIN INHIBITORS AND NITRIC OXIDE MODULATORS | PANMIRA PHARMACEUTICALS, LLC | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068301-A1 | COMPOSITIONS AND TREATMENTS COMPRISING 5-LIPOXYGENASE-ACTIVATING PROTEIN INHIBITORS AND NITRIC OXIDE MODULATORS | ALOX5, ALOX15B, PTGIS | ALOX5 1/4885ALOX5AP 5/4885PTGES2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.