Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917777 | 0.88 | MCHR1 (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5007613 | 0.87 | MCHR1 (0.43) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5006650 | 0.80 | MCHR1 (0.43) | KDM4EALDH1A1ACHEMCHR1 | |
| Hydrochloric Acid SCHEMBL4283833 | 0.79 | MCHR1 (0.42) | KDM4EALDH1A1ACHEMCHR1 | |
| SCHEMBL13448590 | 0.78 | PPARG (0.38) | MEN1KMT2APPARGPPARDPPARA | |
| SCHEMBL3927696 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL10017899 | 0.74 | RAB9A (0.41) | MEN1KMT2AKDM4EMAPTMCHR1 | |
| SCHEMBL3917098 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5007531 | 0.73 | MAOB (0.47) | ACHEMCHR1MAOB | |
| SCHEMBL5004141 | 0.70 | SPHK2 (0.46) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027424-A2 | 9-SUBSTITUTED PHENANTHRENE BASED TYLOPHORINE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-03-11 | — | — | WO | disclosed |