Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MRGPRX1 | Q96LB2 | 10/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449296 | 0.88 | ALDH1A1 (0.54) | MAPTKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL8435221 | 0.74 | PYGL (0.58) | MAPTMRGPRX1KMT2AALDH1A1GAA | |
| SCHEMBL15589735 | 0.73 | ANO1 (0.41) | MAPTAVPR2AVPR1AKMT2AGAA | |
| SCHEMBL26840813 | 0.73 | ALDH1A1 (0.55) | MAPTALDH1A1GAAL3MBTL1MAPK1 | |
| SCHEMBL1121447 | 0.72 | ALDH1A1 (0.65) | MAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL26840803 | 0.72 | ALDH1A1 (0.54) | MAPTKMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL3138705 | 0.70 | PYGL (0.57) | MAPTHDAC1HDAC8HDAC6AVPR2 | |
| SCHEMBL3135239 | 0.70 | PYGL (0.69) | MAPTHDAC8AVPR2AVPR1AKMT2A | |
| SCHEMBL3134272 | 0.70 | ALDH1A1 (0.58) | MAPTHDAC8AVPR2AVPR1AKMT2A | |
| SCHEMBL17535846 | 0.70 | ALDH1A1 (0.58) | MAPTKMT2AALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687494-B2 | Substituted spirobenzazepines | JANSSEN PHARMACEUTICA NV (BE) | 2010-03-30 | — | — | US | disclosed |