SCHEMBL13449754

SCHEMBL13449754

CC1C=CCC(C)(C)C1C(=O)CC(C)N(CCO)Cc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.34
CYP2D6 P10635 3/20 0.34
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
SCN1A P35498 2/20 0.34
SCN2A Q99250 2/20 0.34
SCN3A Q9NY46 2/20 0.34
CYP2C19 P33261 2/20 0.34
SIGMAR1 Q99720 1/20 0.34
SLC22A2 O15244 1/20 0.34
SLC22A1 O15245 1/20 0.34
SLC22A3 O75751 1/20 0.34
ESR1 P03372 1/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2B P18089 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1886586 0.71 LMNA (0.43) TSHRCYP2D6ALDH1A1SMN1; SMN2SCN1A
SCHEMBL3931095 0.68 SIGMAR1 (0.53) TSHRCYP2D6ALDH1A1SMN1; SMN2SCN1A
SCHEMBL18794918 0.67
SCHEMBL1887608 0.67
Ammonia Solution, Strong SCHEMBL16443517 0.66
SCHEMBL9111670 0.64 KMT2A (0.50) TSHRCYP2D6ALDH1A1SMN1; SMN2SCN1A
SCHEMBL19958436 0.64 ALDH1A1 (0.74) TSHRCYP2D6ALDH1A1SMN1; SMN2SCN1A
SCHEMBL18007422 0.63
SCHEMBL16443902 0.63
SCHEMBL4855911 0.63 BCHE (0.50) TSHRCYP2D6ALDH1A1SMN1; SMN2SCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1185239-B1 PRO-FRAGRANCES PROCTER & GAMBLE (US) 2010-03-10 EP disclosed