SCHEMBL1345182

SCHEMBL1345182

c1ccc(C2=NCCN2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 11/20 1.00
CYP1A2 P05177 4/20 0.57
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
ALOX15 P16050 1/20 0.54
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
LMNA P02545 2/20 0.53
PMP22 Q01453 1/20 0.53
POLB P06746 1/20 0.50
CCR1 P32246 1/20 0.50
CCR5 P51681 1/20 0.50
CCR8 P51685 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30373758 1.00 NISCH (1.00) NISCHCYP1A2KDM4EALDH1A1CYP3A4
SCHEMBL2781659 0.85 NISCH (0.74) NISCHCYP1A2ALDH1A1LMNAADRA1A
SCHEMBL9375560 0.76 NISCH (0.61) NISCHCYP1A2KDM4E
SCHEMBL27612098 0.74 NISCH (0.59) NISCHCYP1A2KDM4EALDH1A1CYP3A4
SCHEMBL9412939 0.74 NISCH (0.59) NISCHCYP1A2KDM4EALDH1A1CYP3A4
SCHEMBL9579892 0.74 NISCH (0.81) NISCH
SCHEMBL8887144 0.73 NISCH (0.66) NISCHCYP1A2KDM4EADRA1DADRA1A
SCHEMBL105024 0.72 NISCH (1.00) NISCHCYP1A2ALDH1A1LMNA
Dipyridyl SCHEMBL6885910 0.72 KDM4E (0.93) NISCHCYP1A2KDM4EALDH1A1ALOX15
Dipyridyl SCHEMBL8655605 0.72 KDM4E (0.93) NISCHCYP1A2KDM4EALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230080532-A1 SUPER ABSORBENT POLYMER AND A METHOD OF INCREASING SUGAR CONTENT IN PLANTS UPL LTD (IN) 2023-03-16 US claimed
CN-113646410-A Superabsorbent polymers and methods for increasing sugar content in plants UPL有限公司 2021-11-12 CN claimed
WO-2020202092-A1 SUPER ABSORBENT POLYMER AND A METHOD OF INCREASING SUGAR CONTENT IN PLANTS UPL LTD (IN) 2020-10-08 WO claimed
CN-107501055-B Method for preparing fluoro-olefin compound based on nickel catalysis 中国科学技术大学 2020-08-25 CN claimed
EP-0933362-B1 A process for the preparation of pyridine dicarboxylate derivatives BASF AG (DE) 2002-04-03 EP claimed
US-6222100-B1 CULTIVATING A MONOCOTYLEDONOUS PLANT WHICH IS RESISTANT TO 2-(2-IMIDAZOLIN-2-YL)PYRIDINE HERBICIDE OR DERIVATIVE BECAUSE OF ALTERED ACETOHYDROXYACID SYNTHASE MGI PHARMA, INC. 2001-04-24 US claimed
US-6211439-B1 FOR CROPS WHICH ARE RESISTANT TO HERBICIDES, AND WHICH GENETICALLY TRANSMIT THIS CHARACTERISTIC TO THEIR PROGENY MGI PHARMA, INC 2001-04-03 US claimed
US-6211438-B1 FOR CROPS WHICH ARE RESISTANT TO HERBICIDES, AND WHICH GENETICALLY TRANSMIT THIS CHARACTERISTIC TO THEIR PROGENY MGI PHARMA, INC. 2001-04-03 US claimed
EP-0933362-A1 A process for the preparation of pyridine dicarboxylate derivatives American Cyanamid Company (US) 1999-08-04 EP claimed
EP-0434965-B1 Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof AMERICAN CYANAMID CO (US) 1998-05-20 EP claimed
EP-0434965-A2 Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
US-4791201-A REACTING AN IMIDAZOLINYL PYRIDINE OR QUINOLENE CARBOXYLIC ACID ESTER WITH A FORMAHIDE AND PHOSGENE, THIONYL CHLORIDE, OR PHOSPHORUS OXYCHLORIDE AMERICAN CYANAMID COMPANY (US) 1988-12-13 US claimed
US-4761373-A ACETOHYDROXYACID SYNTHASE ENZYME MOLECULAR GENETICS, INC. (US) 1988-08-02 US claimed
US-4758667-A Process for the preparation of 2-(imidazolin-2-yl)-3-pyridine- and -3-quinolinecarboxylic acids CIBA-GEIGY CORPORATION (US) 1988-07-19 US claimed
US-4698092-A 5H-imidazo[2',1':4,3]imidazo-[1,5a]pyridin-6-ium salts and their use as herbicidal agents AMERICAN CYNAMID COMPANY (US) 1987-10-06 US claimed
US-4695613-A EPOXY RESIN, CYCLIC AMIDINE NEUTRALIZED OLIGOESTER HUELS AKTIENGESELLSCHAFT (DE) 1987-09-22 US claimed
EP-0233150-A2 Process for the preparation of 2-(Imidazolin-2-yl)-pyridine and like quinoline-3-carboxylic acids CIBA-GEIGY AG (CH) 1987-08-19 EP claimed
EP-0231800-A2 Herbicidal pyridinum inner salts and ylides AMERICAN CYANAMID COMPANY (US) 1987-08-12 EP claimed
EP-0154204-A2 Herbicide resistance in plants MGI PHARMA, INC. (US) 1985-09-11 EP claimed
US-4246394-A PROMOTER FOR CROSSLINKING VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) 1981-01-20 US claimed