Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 15/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9412972 | 0.92 | NISCH (0.51) | NISCHKDM4ECYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL1345182 | 0.74 | NISCH (1.00) | NISCHKDM4ECYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL30373758 | 0.74 | NISCH (1.00) | NISCHKDM4ECYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL29442588 | 0.71 | GOT1 (0.46) | KDM4ECYP1A2ALDH1A1ALOX15LMNA | |
| SCHEMBL30792004 | 0.71 | GOT1 (0.46) | KDM4ECYP1A2ALDH1A1ALOX15LMNA | |
| SCHEMBL1456807 | 0.71 | GOT1 (0.46) | KDM4ECYP1A2ALDH1A1ALOX15LMNA | |
| SCHEMBL30382961 | 0.70 | NISCH (0.56) | NISCHKDM4ECYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL9579892 | 0.69 | NISCH (0.81) | NISCH | |
| SCHEMBL3742115 | 0.68 | NISCH (0.56) | NISCHLMNA | |
| SCHEMBL5476725 | 0.68 | NISCH (0.79) | NISCHCYP1A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595011-A1 | Imidazolinyl-pyridazides, their use as herbicides | BAYER AG (DE) | 1994-05-04 | — | — | EP | claimed |
| JP-6228135-A | — | — | None | — | — | JP | disclosed |
| JP-H06228135-A | IMIDAZOLINYL-PYRIDAZINES | BAYER AG | 1994-08-16 | — | — | JP | disclosed |
| EP-0595011-A1 | Imidazolinyl-pyridazides, their use as herbicides | BAYER AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0595011-A1 | Imidazolinyl-pyridazides, their use as herbicides | BAYER AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0595011-A1 | Imidazolinyl-pyridazides, their use as herbicides | BAYER AG (DE) | 1994-05-04 | — | — | EP | disclosed |