SCHEMBL105024

SCHEMBL105024

c1ccc(C2=NCCN2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 12/20 1.00
GAA P10253 1/20 0.77
TSHR P16473 1/20 0.77
ALDH1A1 P00352 1/20 0.73
CYP1A2 P05177 1/20 0.73
HPGD P15428 1/20 0.73
CASP1 P29466 1/20 0.73
CASP7 P55210 1/20 0.73
HSD17B10 Q99714 1/20 0.73
LMNA P02545 1/20 0.62
RECQL P46063 1/20 0.62
MAOB P27338 1/20 0.61
TOP2A P11388 1/20 0.60
TOP2B Q02880 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28772851 0.98 NISCH (0.96) NISCHGAATSHRALDH1A1CYP1A2
Bromide SCHEMBL29039569 0.98 NISCH (0.96) NISCHGAATSHRALDH1A1CYP1A2
Ammonia Solution, Strong SCHEMBL7104964 0.98 NISCH (0.96) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL8141372 0.96 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL28515381 0.92 NISCH (0.85) NISCHGAATSHRALDH1A1CYP1A2
Alcohol SCHEMBL28563093 0.89 NISCH (0.79) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL5476725 0.88 NISCH (0.79) NISCHALDH1A1CYP1A2HPGDCASP1
SCHEMBL28215309 0.87 NISCH (0.76) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL6365864 0.87 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL24495491 0.86 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3992 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037138-A Modified epoxy resin, preparation method thereof, epoxy plastic package material and application 深圳先进电子材料国际创新研究院 2026-05-15 CN claimed
US-12408639-B1 Artificial reef GUILIN UNIVERSITY OF TECHNOLOGY (CN) 2025-09-09 US claimed
US-12398280-B2 Curable coating material for non-impact printing TIGER COATINGS GMBH & CO. KG (AT) 2025-08-26 US claimed
US-20250243381-A1 Composition JOTUN A/S (NO) 2025-07-31 US claimed
EP-4556534-A1 COATING COMPOSITION Jotun A/S (NO) 2025-05-21 EP claimed
WO-2025098994-A1 COATING COMPOSITION JOTUN A/S (NO) 2025-05-15 WO claimed
CN-119979129-A Cooling liquid, preparation method thereof, battery and power utilization device 宁德时代新能源科技股份有限公司 2025-05-13 CN claimed
CN-119973459-A Low-residue lead-free solder paste and preparation method thereof 深圳市同方电子新材料有限公司 2025-05-13 CN claimed
CN-117070130-B Preparation method of epoxy resin-based powder coating with texture effect 黄山天马新材料科技有限公司 2025-04-15 CN claimed
CN-119798680-A Trapezoidal phosphorus-containing polyborosiloxane flame retardant, and preparation method and application thereof 江西广臻感光材料有限公司 2025-04-11 CN claimed
EP-0044030-B1 METHOD OF PREPARING EPOXY RESIN POWDER COATINGS WITH CURING AGENTS BASED ON MONOSALTS OF AROMATIC POLYCARBOXYLIC ACIDS CHEMISCHE WERKE HÜLS AG (DE) 1984-10-03 EP claimed
US-4322327-A Slow-curing water-curable urethane prepolymer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1982-03-30 US claimed
US-4230789-A SUBSTITUTED IMIDAZOLINE ACID NEUTRALIZERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-10-28 US claimed
US-4176142-A Powder coating composition WESTERN ELECTRIC COMPANY, INC. (US) 1979-11-27 US claimed
US-4143181-A TWO LAYERS OF CROSSLINKED HYDROXYLATED MATERIAL SOCIETE FRANCAISE DUCO (FR) 1979-03-06 US claimed
EP-0000418-A1 Process for glueing materials CHEMISCHE WERKE HÜLS AG (DE) 1979-01-24 EP claimed
US-4066625-A CURING AGENTS AMICON CORPORATION (US) 1978-01-03 US claimed
US-4060655-A EPOXY RESIN HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-29 US claimed
US-4007299-A 1,2-EPOXY COMPOUND, POLYCARBOXYLATE VEBA-CHEMIE AG (DT) 1977-02-08 US claimed
US-3947384-A EPOXY COMPOUND, POLYCARBOXYLIC ACID AND CYCLIC AMIDINE VEBA-CHEMIE AKTIENGESELLSCHAFT (DT) 1976-03-30 US claimed