Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452817 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2AGAAGOT1ALDH1A1 | |
| SCHEMBL13452822 | 0.72 | — | — | |
| SCHEMBL30829395 | 0.68 | MEN1 (0.44) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL545454 | 0.67 | MEN1 (0.53) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL29490140 | 0.67 | MEN1 (0.53) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL13452747 | 0.67 | ADORA2A (0.47) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL13417456 | 0.65 | MEN1 (0.41) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL13417461 | 0.64 | MEN1 (0.40) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL13951873 | 0.64 | MEN1 (0.40) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL345211 | 0.64 | GOT1 (0.62) | MEN1KMT2AGOT1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671166-B2 | High internal free volume compositions for low-k dielectric and other applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20070117954-A1 | High internal free volume compositions for low-k dielectric and other applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-24 | — | — | US | disclosed |