SCHEMBL13454331

SCHEMBL13454331

Nc1c(N)c(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c2nsnc2c1-c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
APP P05067 1/20 0.35
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPC1 O15118 1/20 0.33
JAK2 O60674 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22931692 0.85 ALDH1A1 (0.38) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL28935937 0.84 MAPT (0.38) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL13276007 0.84 MAPT (0.41) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL21797210 0.84 SIGMAR1 (0.34) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL18083022 0.83 ALDH1A1 (0.37) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL20200031 0.82 ALDH1A1 (0.36) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL20837193 0.81 MAPT (0.47) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL17173800 0.81 ALDH1A1 (0.35) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL15086101 0.81 KDM4E (0.35) MAPTALDH1A1KDM4EL3MBTL1TDP1
SCHEMBL15871065 0.80 MAPT (0.46) MAPTALDH1A1KDM4EL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507247-B Amphiphilic gadolinium complex and nano micelle for realizing diagnosis and treatment integration 华南理工大学 2023-08-11 CN disclosed
CN-111939124-B Metal polymer, metal polymer nano micelle, and preparation method and application thereof 东南大学 2022-06-28 CN disclosed
CN-114507247-A Amphiphilic gadolinium complex and nano micelle for realizing diagnosis and treatment integration 华南理工大学 2022-05-17 CN disclosed
US-10840397-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2020-11-17 US disclosed
US-10840397-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2020-11-17 US disclosed
CN-111939124-A Metal polymer, metal polymer nano micelle, and preparation method and application thereof 东南大学 2020-11-17 CN disclosed
US-10804472-B2 Light-emitting element, light-emitting device, light source, authentication device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2020-10-13 US disclosed
US-10461201-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2019-10-29 US disclosed
US-10461201-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2019-10-29 US disclosed
US-10431761-B2 Light-emitting element, light-emitting device, authentication device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2019-10-01 US disclosed
US-20130168654-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2013-07-04 US disclosed
US-20130168654-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2013-07-04 US disclosed
US-20130037784-A1 THIADIAZOLE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20130037784-A1 THIADIAZOLE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20130037785-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20130037785-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20120267615-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2012-10-25 US disclosed
US-20120267615-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2012-10-25 US disclosed
US-20120262057-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2012-10-18 US disclosed
US-20120262057-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2012-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120262057-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS RIF1, HRH1, HRH3 MAPT 4037/4885ALDH1A1 25/4885KDM4E 3617/4885
US-20130037784-A1 THIADIAZOLE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE CYP3A4, CYP2E1, TH MAPT 3092/4885ALDH1A1 178/4885KDM4E 2329/4885
US-10431761-B2 Light-emitting element, light-emitting device, authentication device, and electronic apparatus CYBA, AAAS, UGT1A8 MAPT 3159/4885ALDH1A1 115/4885KDM4E 2224/4885
US-20120267615-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE CYP2C19, CYP2C9, AADAC MAPT 3139/4885ALDH1A1 46/4885KDM4E 2887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.