SCHEMBL20200031

SCHEMBL20200031

c1ccc(N(c2ccccc2)c2ccc(-c3c4nccnc4c(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)c4nsnc34)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
APP P05067 1/20 0.34
CYP11B1 P15538 1/20 0.33
MEN1 O00255 1/20 0.32
CRHBP P24387 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
CRHR2 Q13324 1/20 0.32
TLR9 Q9NR96 1/20 0.32
TNK2 Q07912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22361610 0.90 KDM4E (0.30) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL24092688 0.90 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL15672171 0.84 DHFR (0.36) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL19104413 0.84 PDPK1 (0.36) ALDH1A1KDM4EMAPT
SCHEMBL22361628 0.84 ALOX5 (0.30)
SCHEMBL22931692 0.83 ALDH1A1 (0.38) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL15086101 0.83 KDM4E (0.35) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL13454331 0.82 MAPT (0.46) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL18083022 0.82 ALDH1A1 (0.37) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL13555447 0.81 ADK (0.37) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220135874-A1 INFRARED-EMITTING COMPOUND, AND LUMINESCENT THIN FILM, LUMINESCENT PARTICLE, WAVELENGTH CONVERSION FILM AND INFRARED-EMITTING SURFACE LIGHT SOURCE CONTAINING SAME Konica Minolta, Inc. (JP) 2022-05-05 US disclosed
US-20210380607-A1 INFRARED ABSORBERS, INFRARED ABSORBING/BLOCKING FILMS AND PHOTOELECTRIC DEVICES, SENSORS, AND ELECTRONIC DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-09 US disclosed
US-20210159423-A1 NEAR-INFRARED ABSORBERS, NEAR-INFRARED ABSORBING/BLOCKING FILMS, PHOTOELECTRIC DEVICES, ORGANIC SENSORS, AND ELECTRONIC DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-27 US disclosed
US-10228328-B2 Organic electro-luminescent element and bioinstrumentation device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-03-12 US disclosed
US-20190058132-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-21 US disclosed
US-20180149595-A1 ORGANIC ELECTRO-LUMINESCENT ELEMENT AND BIOINSTRUMENTATION DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-31 US disclosed
US-20180151810-A1 ORGANIC ELECTRO-LUMINESCENT ELEMENT AND BIOINSTRUMENTATION DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-31 US disclosed
US-20180151810-A1 ORGANIC ELECTRO-LUMINESCENT ELEMENT AND BIOINSTRUMENTATION DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-31 US disclosed
US-20180149595-A1 ORGANIC ELECTRO-LUMINESCENT ELEMENT AND BIOINSTRUMENTATION DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380607-A1 INFRARED ABSORBERS, INFRARED ABSORBING/BLOCKING FILMS AND PHOTOELECTRIC DEVICES, SENSORS, AND ELECTRONIC DEVICES CRY1, CRY2, CCNT1 ALDH1A1 82/4885L3MBTL1 2527/4885KDM4E 3554/4885
US-20210159423-A1 NEAR-INFRARED ABSORBERS, NEAR-INFRARED ABSORBING/BLOCKING FILMS, PHOTOELECTRIC DEVICES, ORGANIC SENSORS, AND ELECTRONIC DEVICES CRY1, CRY2, RXFP4 ALDH1A1 136/4885L3MBTL1 2901/4885KDM4E 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.