Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426 | 0.86 | LMNA (0.42) | MAPTPTPN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11897018 | 0.85 | SMN1; SMN2 (0.49) | L3MBTL1SLC6A9LPAR1MAPTKDM4E | |
| SCHEMBL14792978 | 0.85 | PLA2G2A (0.46) | L3MBTL1IP6K1SLC6A9LPAR1MAPT | |
| SCHEMBL5776962 | 0.84 | NR4A2 (0.51) | L3MBTL1IP6K1SLC6A9LPAR1MAPT | |
| SCHEMBL18597840 | 0.82 | LPAR1 (0.50) | IP6K1SLC6A9LPAR1MAPTALDH1A1 | |
| SCHEMBL14792983 | 0.80 | ALDH1A1 (0.46) | L3MBTL1IP6K1SLC6A9LPAR1MAPT | |
| SCHEMBL5773143 | 0.79 | FFAR4 (0.51) | SLC6A9MAPTKDM4EGAAPTPN1 | |
| SCHEMBL13435 | 0.77 | BRD4 (0.43) | L3MBTL1IP6K1SLC6A9LPAR1MAPT | |
| SCHEMBL3075233 | 0.77 | ALDH1A1 (0.48) | L3MBTL1SLC6A9LPAR1MAPTKDM4E | |
| SCHEMBL14792982 | 0.77 | BRD4 (0.40) | L3MBTL1SLC6A9MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041462-A2 | POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |