Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.64 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.51 |
| ▸ | LCK | P06239 | 6/20 | 0.51 |
| ▸ | ITK | Q08881 | 6/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265115 | 0.85 | ABL1 (0.55) | ROCK2ITKFFAR2 | |
| SCHEMBL13457370 | 0.83 | ROCK2 (0.57) | ROCK2OTUD7BUSP30LCKITK | |
| SCHEMBL16712958 | 0.79 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL4662575 | 0.77 | ROCK2 (0.76) | ROCK2 | |
| SCHEMBL13457496 | 0.75 | SMN1; SMN2 (0.62) | ROCK2OTUD7BUSP30LCKITK | |
| SCHEMBL13457222 | 0.74 | LCK (0.62) | USP30LCKITK | |
| SCHEMBL6068368 | 0.74 | ABL1 (0.71) | ROCK2LCKITK | |
| SCHEMBL1254574 | 0.74 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL8739816 | 0.73 | LCK (0.53) | ROCK2OTUD7BUSP30LCKITK | |
| SCHEMBL23221371 | 0.72 | PCSK9 (0.55) | ROCK2OTUD7BUSP30LCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |