Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
| ▸ | WNT3A | P56704 | 3/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | PRKCG | P05129 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457481 | 0.85 | ROCK2 (0.64) | ITKFFAR2ROCK2 | |
| SCHEMBL13457067 | 0.76 | MAPT (0.65) | ABL1ITKWNT3ACYP3A4MEN1 | |
| SCHEMBL3877305 | 0.76 | PIK3CG (0.78) | ABL1PIK3CGDYRK1AFSCN1PIK3CA | |
| SCHEMBL16896934 | 0.71 | ACP1 (0.71) | ACP1DYRK1ACSNK1DMEN1KMT2A | |
| SCHEMBL18205121 | 0.71 | ACP1 (0.71) | ACP1DYRK1ACSNK1DMEN1KMT2A | |
| SCHEMBL6068110 | 0.71 | ABL1 (0.80) | ABL1PIK3CGCASP3SENP7SENP8 | |
| SCHEMBL13457568 | 0.70 | ABL1 (0.64) | ABL1ITKCASP3SENP7SENP8 | |
| SCHEMBL13457119 | 0.70 | LRRK2 (0.64) | ABL1ITKWNT3APIK3CGMEN1 | |
| SCHEMBL25644968 | 0.70 | ABL1 (0.62) | ABL1ITKWNT3APIK3CGCASP3 | |
| SCHEMBL13457004 | 0.69 | HTT (0.65) | ABL1WNT3APIK3CGPIK3CACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |