Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303841 | 0.81 | AHR (0.58) | AHRCYP11B2NUDT1 | |
| SCHEMBL28530395 | 0.78 | AHR (0.54) | AHRCYP11B2NUDT1 | |
| SCHEMBL30676207 | 0.73 | AHR (0.78) | AHRCYP11B2NUDT1 | |
| SCHEMBL30601204 | 0.72 | AHR (1.00) | AHRCYP11B2 | |
| SCHEMBL18341116 | 0.72 | AHR (0.49) | AHRCYP11B2NUDT1 | |
| SCHEMBL7851628 | 0.72 | AHR (0.49) | AHRCYP11B2 | |
| SCHEMBL28485655 | 0.71 | AHR (0.47) | AHRCYP11B2NUDT1 | |
| SCHEMBL13457591 | 0.71 | NUDT1 (0.34) | AHRNUDT1 | |
| SCHEMBL3266110 | 0.70 | JAK2 (0.55) | AHR | |
| SCHEMBL2185953 | 0.68 | EGLN2 (0.57) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |