Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544044 | 0.80 | EGLN2 (0.48) | NUDT1KDM4EPDE10A | |
| SCHEMBL13457590 | 0.71 | AHR (0.56) | NUDT1AHR | |
| SCHEMBL7915878 | 0.68 | ALDH1A1 (0.33) | KDM4E | |
| SCHEMBL32679961 | 0.68 | DYRK1A (0.43) | KDM4E | |
| SCHEMBL3304862 | 0.66 | EGLN2 (0.32) | — | |
| SCHEMBL7870289 | 0.63 | RAB9A (0.37) | KDM4EPDE10A | |
| SCHEMBL7871598 | 0.62 | GAA (0.38) | KDM4E | |
| SCHEMBL30485249 | 0.62 | NUDT1 (0.33) | NUDT1PDE10AAHR | |
| SCHEMBL13390528 | 0.62 | NUDT1 (0.51) | NUDT1KDM4EPDE10A | |
| SCHEMBL18366670 | 0.62 | PDE10A (0.42) | NUDT1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |