Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13390440 | 0.76 | CYP11B2 (0.53) | AHRCYP11B2 | |
| SCHEMBL25074680 | 0.76 | AHR (0.39) | AHRNUDT1CYP11B2KMT2A | |
| SCHEMBL2252581 | 0.76 | NUDT1 (0.65) | AHRNUDT1EGLN2JAK1 | |
| SCHEMBL3300152 | 0.76 | AHR (0.36) | AHRNUDT1CYP11B2KMT2A | |
| SCHEMBL3299884 | 0.74 | HDAC4 (0.37) | AHRNUDT1JAK1KMT2A | |
| SCHEMBL2252969 | 0.72 | EGLN2 (0.54) | AHRNUDT1EGLN2JAK1 | |
| SCHEMBL3302899 | 0.72 | AHR (0.36) | AHRNUDT1CYP11B2 | |
| SCHEMBL12078961 | 0.69 | AHR (0.34) | AHRCYP11B2 | |
| SCHEMBL3306690 | 0.68 | AHR (0.31) | AHR | |
| SCHEMBL21306411 | 0.67 | L3MBTL1 (0.41) | AHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344494-B1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARM LLC (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |