Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690695 | 0.87 | MAPK14 (0.31) | MAPK14 | |
| SCHEMBL1847413 | 0.84 | MAPK14 (0.39) | MAPK14TP53MAPTSMN1; SMN2 | |
| SCHEMBL15743695 | 0.80 | POLB (0.36) | GABRA1GABRB2 | |
| SCHEMBL15086934 | 0.79 | MAPK14 (0.33) | MAPK14TP53MAPTSMN1; SMN2 | |
| SCHEMBL689550 | 0.77 | POLB (0.34) | MAPT | |
| SCHEMBL28756085 | 0.76 | ALDH1A1 (0.43) | MAPK14MAPTSMN1; SMN2 | |
| SCHEMBL29639434 | 0.76 | ALDH1A1 (0.43) | MAPK14MAPTSMN1; SMN2 | |
| SCHEMBL10233040 | 0.75 | MAPT (0.39) | MAPK14TP53MAPTSMN1; SMN2GABRA1 | |
| SCHEMBL15086981 | 0.74 | KDM4E (0.41) | MAPK14TP53MAPTSMN1; SMN2 | |
| SCHEMBL10233191 | 0.72 | MAPK14 (0.35) | MAPK14TP53MAPTSMN1; SMN2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |