SCHEMBL134586

SCHEMBL134586

[CH2][C@@]1(C)CCC[C@]2(C)c3ccc(C(C)C)cc3CC[C@@H]12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 0.69
▸ KARS1 Q15046 4/20 0.69
▸ MEN1 O00255 3/20 0.69
▸ KMT2A Q03164 3/20 0.69
▸ TSHR P16473 2/20 0.69
▸ CYP2D6 P10635 2/20 0.69
▸ CYP2C19 P33261 2/20 0.69
▸ PDK1 Q15118 1/20 0.69
▸ PDK2 Q15119 1/20 0.69
▸ PDK3 Q15120 1/20 0.69
▸ PDK4 Q16654 1/20 0.69
▸ CYP2C9 P11712 1/20 0.69
▸ MAPK1 P28482 2/20 0.67
▸ TP53 P04637 1/20 0.67
▸ MAPT P10636 1/20 0.67
▸ ALOX15 P16050 1/20 0.67
▸ RXRA P19793 1/20 0.67
▸ CCNE1 P24864 1/20 0.67
▸ CDK2 P24941 1/20 0.67
▸ RXRB P28702 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6319702 1.00 CYP3A4 (0.69) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL6319708 0.87 CYP3A4 (0.72) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL15899658 0.87 CYP3A4 (0.72) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL6280790 0.87 CYP3A4 (0.72) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL20866406 0.85 CYP3A4 (0.72) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL18019013 0.83 KARS1 (0.79) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL18431215 0.82 CYP3A4 (0.66) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL22476430 0.82 CYP3A4 (0.66) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL9775101 0.82 CYP3A4 (0.66) CYP3A4KARS1MEN1KMT2ATSHR
SCHEMBL16298228 0.82 CYP3A4 (0.80) CYP3A4KARS1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344278-A Rosin amino acid compound and preparation method and application thereof 广西中医药大学 2024-07-16 — — CN claimed
CN-117551000-A Dehydroabietyl acid group aggregation-induced red light compound, preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2024-02-13 — — CN claimed
CN-114539159-B Dehydroabietyl Schiff base multi-ion functional fluorescent probe and preparation method and application thereof 南京林业大学 2023-12-01 — — CN claimed
CN-116217429-A Dehydroabietyl acid anilide compound acting with DNA as well as preparation method and application thereof 南京林业大学 2023-06-06 — — CN claimed
CN-114349532-B Liquid preparation for early curing of concrete and early curing method of concrete 北京易晟元环保工程有限公司 2023-03-24 — — CN claimed
CN-114349532-A Liquid preparation for early curing of concrete and early curing method of concrete 北京易晟元环保工程有限公司 2022-04-15 — — CN claimed
US-20210369702-A1 METHODS FOR TREATING ANEMIA IN SUBJECTS HAVING KIDNEY FAILURE USING INHIBITORS OF HYPOXIA-INDUCIBLE FACTOR (HIF) HYDROXYLASE FIBROGEN, INC. (US) 2021-12-02 — — US claimed
US-10927081-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-02-23 — — US claimed
US-10894774-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-01-19 — — US claimed
US-10882827-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-01-05 — — US claimed
US-4948813-A Benzylketone phospholipase A2 inhibitors E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-14 — — US claimed
US-4921571-A ALKANE SULFONIC ACID, INORGANIC NITRATE, INHIBITOR, PRINTED CIRCUIT BOARDS MACDERMID, INCORPORATED (US) 1990-05-01 — — US claimed
US-4707189-A Biostable compositions and the aqueous solutions thereof as thickeners for aqueous-based systems HERCULES INCORPORATED (US) 1987-11-17 — — US claimed
US-4596863-A Maleic anhydride-alpha, beta unsaturated compound BAYER AKTIENGESELLSCHAFT (DE) 1986-06-24 — — US claimed
EP-0104528-B1 REACTIVE SIZING AGENT FOR PAPER BAYER AG (DE) 1985-11-13 — — EP claimed
US-4205995-A Pigment compositions CIBA-GEIGY CORPORATION (US) 1980-06-03 — — US claimed
EP-0010842-A1 Polyurethane foam and method of preparation thereof UNIROYAL LTD. (CA) 1980-05-14 — — EP claimed
US-4171309-A Process for the preparation of a solvent-stable, red-shade copper phthalocyanine pigment composition CIBA-GEIGY CORPORATION (US) 1979-10-16 — — US claimed
US-4135944-A PIGMENT COMPOSITION CIBA-GEIGY CORPORATION (US) 1979-01-23 — — US claimed
US-4110109-A Oxidation inhibition of steel wool in silver recovery MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-29 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369702-A1 METHODS FOR TREATING ANEMIA IN SUBJECTS HAVING KIDNEY FAILURE USING INHIBITORS OF HYPOXIA-INDUCIBLE FACTOR (HIF) HYDROXYLASE HIF1AN, HIF1A, EGLN2 CYP3A4 3235/4885KARS1 2365/4885MEN1 3699/4885
US-10894774-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC CYP3A4 3402/4885KARS1 3327/4885MEN1 3714/4885
US-10927081-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC CYP3A4 3402/4885KARS1 3327/4885MEN1 3714/4885
US-10882827-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC CYP3A4 3073/4885KARS1 3829/4885MEN1 3852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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