Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | YES1 | P07947 | 4/20 | 0.46 |
| ▸ | PIM1 | P11309 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | HIPK1 | Q86Z02 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458735 | 0.99 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL13458979 | 0.88 | KDM4E (0.73) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL13458946 | 0.87 | MELK (0.55) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL13458828 | 0.86 | KDM4E (0.74) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL3358457 | 0.82 | ACACA (0.50) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL3358750 | 0.82 | ACACA (0.50) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL1745982 | 0.82 | ACACA (0.50) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL17899330 | 0.82 | ACACA (0.50) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL3698074 | 0.82 | ACACA (0.50) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL12112655 | 0.81 | ACACA (0.51) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |