Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458828 | 0.99 | KDM4E (0.74) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL13458945 | 0.88 | MAPK1 (0.56) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL13458735 | 0.86 | MAPK1 (0.57) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL13458946 | 0.86 | MELK (0.55) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL18285499 | 0.85 | KDM4E (0.97) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL17899330 | 0.81 | ACACA (0.50) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL3358457 | 0.81 | ACACA (0.50) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL3358750 | 0.81 | ACACA (0.50) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL3698074 | 0.81 | ACACA (0.50) | KDM4EMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL1745982 | 0.81 | ACACA (0.50) | KDM4EMAPTALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |