Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.55 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458945 | 0.87 | MAPK1 (0.56) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL13458979 | 0.86 | KDM4E (0.73) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL13458735 | 0.85 | MAPK1 (0.57) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL13458828 | 0.84 | KDM4E (0.74) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3698074 | 0.80 | ACACA (0.50) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL17899330 | 0.80 | ACACA (0.50) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1745982 | 0.80 | ACACA (0.50) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3358750 | 0.80 | ACACA (0.50) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3358457 | 0.80 | ACACA (0.50) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL12112655 | 0.78 | ACACA (0.51) | KDM4EMAPTL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |